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> Paul Rogers wrote:
>
> > Ken,
> >
> > I think you assume too much if you consider that
> > prostate cancer is
> > primarily caused or promoted by estradiol or
> > estrogens in general.
>
So-called scientific reporting must always viewed with respect to the
context in which it is written. For example, creationalists writing on
evolution do so with a decided bias. In line with Max Planck's
observation that science advances due to the deaths of older
scientists, here's a short piece by Dr HingHua Tsang reporting on the
late Dr John Lee's take on estrodiol and the complex endocrinological
changes associated with aging; omitted is any reference to the
debilitating effects of hidden soy products in the diet, an outcome of
Eastman Kodak bribing Congressmen to remove soy from the toxic foods
list in the mid 1950s.
"Just as in women, men suffer the effects of "estrogen dominance".
"Many researchers including John R. Lee, M.D (Leading pioneer in
natural progesterone therapy), Dr. Jesse Hanley and Dr. Peter Eckhart
are coming to the conclusion that the over abundance of estrogen and
estrogen like substances (xenoestrogens or foreign estrogens) are
responsible for a vast number of today's health problems. This over
abundance of estrogen is referred to as estrogen dominance which is an
increasingly serious problem for both women and men. Dr. Lee believes
that it is excessive exposure to estrogen that is the primary cause of
prostate enlargement and prostate cancer. Xenoestrogens in the
environment are among the culprits. Sources of xenoestrogens includes
commercially raised beef, chicken and pork, birth control pills,
spermacide, detergent, plastics, plastic drinking bottles, pesticides,
herbicides, personal care products, canned foods and lacquers.
"Men produce estrogen (Estradiol) but in much lower amount than women.
Men also produce progesterone, but about half the amount from that of
females. Progesterone is made in men by the adrenal glands and testes.
Progesterone is vital to good health in both women and men. It is the
primary precursor of our adrenal cortical hormones and testosterone.
The male hormone, testosterone, is an antagonist to estradiol (E2). It
is made from progesterone. Men normally continue to produce relatively
normal level of testosterone for their age and well into the
seventies. Contrary to common perception, testosterone does not cause
prostate cancer. Young men have high levels of testosterone and old
men low levels. If testosterone were the cause of prostate cancer,
young men would be dying of prostate cancer. Studies had shown that
men with the highest level of testosterone have the least prostate
enlargement. Conversely, men with the highest level of estrogen have
enlarged prostates. Declining testosterone from aging, together with
increasing level of estrogen, is the most likely reason for prostate
enlargement and cancer in men.
"The prostate is embryologically the same as the uterus in the female.
Research Studies (Listed at the end of this newsletter) have shown
that when prostate cells are exposed to estrogen, the cells
proliferate and become cancerous. When progesterone or testosterone
was added, cancer cell dies. During the aging process, progesterone
level falls in men, especially after age 60. Progesterone is the chief
inhibitor of an enzyme called 5-alpha reductase that is responsible
for converting testosterone to dihydrotestosterone (DHT), a much more
potent derivative that is linked to prostate cancer. When the level of
progesterone falls in men, the amount of conversion from testosterone
to DHT increases. Unfortunately, DHT is not as powerful an inhibitor
of cancer cell compared to testosterone. When the level of
testosterone decreases, the relative level of estradiol in men
increases. Estradiol, turns on BCL2 oncogene (Onco means cancer) and
increases the risk of prostate cancer if adequate amount of
progesterone is not there to counteract its effect by stimulating the
P53 cancer protection gene.
"Benign prostatic hyperplasia (BPH), a prostate enlargement condition,
is a common condition affecting the majority of male above age 50.
Prostate cancer is a leading cause of cancer in men. It is slow
growing, with a doubling time of 5 years. Numerous anecdotal reports
of reduction of BPH and reversal of prostate cancer through the use of
natural progesterone supplementation have been reported."
Lee and others stand as an alternative view to that of medical
orthodoxy. It should be noted that our standard notion of prostate
cancer being associated with testosterone stem from work done in 1940
that would not be publishable today due to its anecdotal nature!
Caveat lector.
best
Ken O'Neill
Austin, Texas
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